Mr. Prabhu D
I am an experienced Animal House Supervisor with extensive expertise in laboratory animal care, preclinical research, and animal facility management. I have been working in the field of laboratory animal science and biomedical research, with hands-on experience in the handling, breeding, monitoring, dosing, anesthesia, sample collection, and maintenance of laboratory animals under GLP-compliant conditions.
My research experience includes developing and maintaining experimental animal models of diabetes, obesity, insulin resistance, diabetic neuropathy, and diabetic nephropathy. I have also contributed to studies involving probiotics, medicinal plants, beta-cell dysfunction, and molecular mechanisms associated with metabolic diseases.
In addition to animal research, I have practical experience in tissue culture, cell-line maintenance, lymphocyte isolation, Western blotting, comet assay, spectrophotometric analysis, tissue collection, and biological sample processing. I have also supported research teams in laboratory management, inventory control, experimental procedures, and student training. My professional interests are focused on contributing to high-quality preclinical and biomedical research while maintaining high standards of animal welfare, laboratory safety, and research quality.
- 2007 - Bachelor’s in economics, University of Madras, Chennai.
- 2011 - Diploma in Medical Lab Technology (DMLT), Academic Board of All India Laboratory Technologist Association-New Delhi.
- 2012 - Laboratory Animal Technician Training Course, National Institute of Nutrition (Indian Council of Medical Research-New Delhi)
- January 2021 to Present: Working as a Research Assistant in the Division of Medical Research, SRM Medical College Hospital and Research Centre, SRMIST, Kattankulathur, Tamilnadu, India.
- January 2011 to January 2021: Worked as a Animal House Supervisor, Department of Cell and Molecular Biology, Madras Diabetes Research Foundation Chennai, Tamilnadu, India.
- September 2005 to August 2011: Worked as a Animal House Keeper, Department of Cell and Molecular Biology, Madras Diabetes Research Foundation Chennai, Tamilnadu, India.
- Laboratory Animal Science and Animal Facility Management
- Experimental Animal Models of Diabetes and Obesity, Insulin Resistance and Metabolic Disorders, Diabetic Neuropathy and Diabetic Nephropathy
- Animal Handling, Breeding, Dosing and Experimental Procedures
- Animal Welfare and GLP-Compliant Laboratory Practices
- Cell Culture and Tissue Culture Techniques
- Molecular and Cellular Biology
- Biological Sample Collection and Processing
- Western Blotting and DNA Damage Assessment
- Biomedical Research Support and Laboratory Management
- Impact of bisphenol a on the levels of vascular calcification biomarkers in type 2 diabetes mellitus with vascular complications: A case-control study;. April 2024, Emerging Contaminants 10(4), DOI:10.1016/j.emcon.2024. 10034, (Impact Factor: 8.2) Mohanraj Nehru, Prasanth Subramaniam, M.S.Jancy, Prabhu Durairaj, J.S. Kumar, Venkataraman Prabhu
- Augmentation of RBP4/STRA6 signaling leads to insulin resistance and inflammation and the plausible therapeutic role of vildagliptin and metformin”. Mol Biol Rep. 2021, May;48(5):4093-4106 (Impact Factor: 3.2).Kuppan Gokulakrishna, Gautam Kumar Pandey, Chandrakumar Sathishkumar, Saravanakumar Sundararajan, Prabhu Durairaj, Nagaraj Manickam, Viswanathan Mohan, Muthuswamy Balasubramanyam.
- Augmentation of histone deacetylase 3 (HDAC3) epigenetic signature at the interface of proinflammation and insulin resistance in patients with type 2 diabetes”. Clin Epigenetics. 2016 Nov 24; 8:125, (IF- 5.7). Sathishkumar C, Prabu P, Balakumar M, Lenin R, Prabhu D, Anjana RM, Mohan V, Balasubramanyam M.
- Improvement in glucose tolerance and insulin sensitivity by probiotic strains of Indian gut origin in high-fat diet-fed C57BL/6J mice. Eur J Nutr. 2016 Oct 18, (Impact Factor: 4.9). Balakumar M, Prabhu D, Sathishkumar C, Prabu P, Rokana N, Kumar R, Raghavan S, Soundarajan A, Grover S, Batish VK, Mohan V, Balasubramanyam M
- High-fructose diet is as detrimental as high-fat diet in the induction of insulin resistance and diabetes mediated by hepatic/pancreatic endoplasmic reticulum (ER) stress. Mol Cell Biochem. 2016 Dec; 423(1-2):93-104. (Impact Factor: 4.7). Balakumar M, Raji L, Prabhu D, Sathishkumar C, Prabu P, Mohan V, Balasubramanyam M
- Increased circulatory levels of lipopolysaccharide (LPS) and zonulin signify novel biomarkers of proinflammation in patients with type 2 diabetes. Mol Cell Biochem. DOI 10.1007/s11010-013-1911-4. (Impact Factor: 4.7). Jayashree , Y. S. Bibin , D. Prabhu , C. S. Shanthirani , K. Gokulakrishnan , B. S. Lakshmi, V. Mohan, M. Balasubramanyam
- Availability: Currently not available
