Dr. Mrinmoy Das

• D. in Immunology (2017) – Sorbonne University / Université Pierre et Marie Curie (UPMC), Paris, France
• Sc. in Biotechnology (2010) – Berhampur University, Odisha, India
• B.Sc. in Microbiology (2008) – Vidyasagar University, West Bengal, India

• 2025-Present: Assistant Professor, Division of Medical Research, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, India
• 2021-2025: Scientist/Instructor, Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, USA
• 2017-2021: Postdoctoral Research Fellow, Boston Children’s Hospital, Harvard Medical School, Boston, USA
• 2014-2017: Doctoral Researcher, Sorbonne University / Université Pierre et Marie Curie (UPMC), Paris, France
• 2011-2014: Junior Research Fellow/Research Technician, Department of Biochemistry, Indian Institute of Science (IISc), Bengaluru, India

• Allergic and inflammatory diseases: atopic dermatitis, asthma, allergic rhinitis, COPD, and food allergy
• Epithelial barrier dysfunction, IgE-mediated immunity, and basophil biology
• Host-pathogen interactions and susceptibility to respiratory infections (URTI & LRTI)
• Skin-gut immune axis and T cell trafficking
• Translational immunology, environmental triggers, and biomarker discovery

• Barrier Immunology
• Allergy and Inflammation
• Mucosal Immunology
• Epithelial Biology
• Skin-Gut Immune Axis
• Host-Microbiota Interactions
• Host-Pathogen Interactions
• Host-Directed Therapeutics

2026

1. Das M #, Geha RS. Basophils in atopic dermatitis: Immunologic roles and clinical implications. Ann Allergy Asthma Immunol. 2026 Feb;136(2):149-157. (# corresponding author)
2. Mokal CN, Das M, Hannenhalli S, Agrawal P. Oral submucosal fibrosis: a comprehensive review on pathogenesis, diagnosis, therapeutics, and computational advances. Front Cell Dev Biol. 2026 Jan 22;13:1754209. 

2025

1. Das M#, Alasharee M, Woods B, Mukherjee S, Kim S, Elkins M, Ngo J, Magin L, Timilshina M, Leyva-Castillo JM, Murphy KM, Anthony RM, Laureano AFS, Murphy GF, McNamee S, Brombacher F, Hogan SP, Turner JR, Abtahi S, Phipatanakul W, Leung DYM, Goleva E, Oettgen HC, Li M, Chou J, Schlievert PM, Finkelman FD, Geha RS. S. aureus exposure during cutaneous antigen sensitization causes basophil- and interleukin-4-dependent exaggerated food anaphylaxis. Immunity. 2025 Nov 11;58(11):2769-2784.e6. (# corresponding author)
2. Mukherjee S, Geha RS, Das M#. The Mechanisms of Immunoglobulin E Sensitizations in Atopic Dermatitis. Immunol Allergy Clin North Am. 2025 Nov;45(4):535-546. (# corresponding author)
3. Janssen E*, Das M*, Butts J, Alasharee M, Mukherjee S, Lozano GL, Rao C, Livingston AF, Woods B, Smith E, Peters Z, Milin E, Beamer MA, Wilkie H, Leyva-Castillo JM, Kam C, Sobh A, Dasouki M, Wakim RH, Dbaibo G, Al-Herz W, Chatila TA, Finkelman FD, Rakoff-Nahoum S, Geha RS. DOCK8 in T cells promotes Th17 and Treg cell functionality to restrain mucosal mast cells and limit susceptibility to oral anaphylaxis. Immunity. 2025 Jul 8;58(7):1794-1810.(* Co-first authors)
4. Chakraborty S, Banerjee P, Joseph JP, Pathak S, Verma T, Karhale AK, Chandra D, Das M, Saha P, Nandi D. Functional loss of rffG and rfbB, encoding dTDP-glucose 4,6-dehydratase, alters colony morphology, cell shape, motility and virulence in Salmonella Typhimurium. Front Microbiol. 2025 May 21;16:1572117.
5. Das M, Keswani T. Editorial: T and B cell immune dynamics in allergic response. Front Allergy. 2025 Feb 12;6:1558724. 
6. Conrad ML, Barrientos G, Cai X, Mukherjee S, Das M, Stephen-Victor E, Harb H. Regulatory T cells and their role in allergic disease. Allergy. 2025 Jan;80(1):77-93. 

2024

1. Leyva-Castillo JM*, Das M*, Strakosha M, McGurk A, Artru E, Kam C, Alasharee M, Wesemann DR, Tomura M, Karasuyama H, Brombacher F, Geha RS. IL-4 acts on skin-derived dendritic cells to promote the TH2 response to cutaneous sensitization and the development of allergic skin inflammation. J Allergy Clin Immunol. 2024 Dec;154(6):1462-1471. (* Co-first authors)
2. Wilkie H, Das M, Pelovitz T, Bainter W, Woods B, Alasharee M, Sobh A, Baris S, Eltan SB, Al-Herz W, Barbouche MR, Ben-Mustapha I, Ben-Ali M, Sallam MTH, Awad A, Lotfy S, El Marsafy A, Ezzelarab M, Farrar M, Schmidt BAR, NandyMazumdar M, Guttman-Yassky E, Sheets A, Vidic KM, Murphy G, Schlievert PM, Chou J, Leyva-Castillo JM, Janssen E, Timilshina M, Geha RS. Regulatory T-cell dysfunction and cutaneous exposure to Staphylococcus aureus underlie eczema in DOCK8 deficiency. J Allergy Clin Immunol. 2024 Jul;154(1):143-156. 
3. Das M, Mukherjee S, Geha RS. Phosphodiesterase 4 Inhibitors, Basophils, and Atopic Dermatitis. J Invest Dermatol. 2024 May;144(5):924-926. 

2023

1. Wilkie H, Timilshina M, Rahmayanti S, Das M, Pelovitz T, Geha RS. DOCK8 is essential for neutrophil mediated clearance of cutaneous S. aureus infection. Clin Immunol. 2023 Sep;254:109681. 
2. Yang B, Wilkie H, Das M, Timilshina M, Bainter W, Woods B, Daya M, Boorgula MP, Mathias RA, Lai P, Petty CR, Weller E, Harb H, Chatila TA, Leung DYM, Beck LA, Simpson EL, Hata TR, Barnes KC, Phipatanakul W, Leyva-Castillo JM, Geha RS. The IL-4Rα Q576R polymorphism is associated with increased severity of atopic dermatitis and exaggerates allergic skin inflammation in mice. J Allergy Clin Immunol. 2023 May;151(5):1296-1306.

2021

1. Leyva-Castillo JM, Das M, Kane J, Strakosha M, Singh S, Wong DSH, Horswill AR, Karasuyama H, Brombacher F, Miller LS, Geha RS. Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection. JCI Insight. 2021 Nov 8;6(21):e149953
2. Bainter W, Lougaris V, Wallace JG, Badran Y, Hoyos-Bachiloglu R, Peters Z, Wilkie H, Das M, Janssen E, Beano A, Farhat KB, Kam C, Bercich L, Incardona P, Villanacci V, Bondioni MP, Meini A, Baronio M, Abarzua P, Parolini S, Tabellini G, Maio S, Schmidt B, Goldsmith JD, Murphy G, Hollander G, Plebani A, Chou J, Geha RS. Combined immunodeficiency with autoimmunity caused by a homozygous missense mutation in inhibitor of nuclear factor 𝛋B kinase alpha (IKKα). Sci Immunol. 2021 Sep 17;6(63):eabf6723. 
3. Das M, Leyva-Castillo JM, Geha RS. Basophil: The cell that itches. J Allergy Clin Immunol. 2021 Sep;148(3):708-709.
4. Leyva-Castillo JM, Das M, Artru E, Yoon J, Galand C, Geha RS. Mast cell-derived IL-13 downregulates IL-12 production by skin dendritic cells to inhibit the TH1 cell response to cutaneous antigen exposure. J Allergy Clin Immunol. 2021 Jun;147(6):2305-2315.

2020

1. Stephen-Victor E, Das M, Karnam A, Pitard B, Gautier JF, Bayry J. Potential of regulatory T-cell-based therapies in the management of severe COVID-19. Eur Respir J. 2020 Sep 3;56(3):2002182. 
2. Janssen E, Tohme M, Butts J, Giguere S, Sage PT, Velázquez FE, Kam C, Milin E, Das M, Sobh A, Al-Tamemi S, Luscinskas FW, Batista F, Geha RS. DOCK8 is essential for LFA-1-dependent positioning of T follicular helper cells in germinal centers. JCI Insight. 2020 Aug 6;5(15):e134508.
3. Das M, Stephen-Victor E, Bayry J. Regulatory T cells do not suppress rather activate human basophils by IL-3 and STAT5-dependent mechanisms. Oncoimmunology. 2020 Jun 5;9(1):1773193. 
4. Karnam A, Rambabu N, Das M, Bou-Jaoudeh M, Delignat S, Käsermann F, Lacroix-Desmazes S, Kaveri SV, Bayry J. Therapeutic normal IgG intravenous immunoglobulin activates Wnt-β-catenin pathway in dendritic cells. Commun Biol. 2020 Mar 4;3(1):96.
5. Galeotti C, Karnam A, Das M, Kaveri SV, Bayry J. Acid Stripping of Surface IgE Antibodies Bound to FcεRI is Unsuitable for the Functional Assays that Require Long-Term Culture of Basophils and Entire Removal of Surface IgE. Int J Mol Sci. 2020 Jan 13;21(2):510. 
6. Das M, Karnam A, Stephen-Victor E, Gilardin L, Bhatt B, Kumar Sharma V, Rambabu N, Patil V, Lecerf M, Käsermann F, Bruneval P, Narayanaswamy Balaji K, Benveniste O, Kaveri SV, Bayry J. Intravenous immunoglobulin mediates anti-inflammatory effects in peripheral blood mononuclear cells by inducing autophagy. Cell Death Dis. 2020 Jan 23;11(1):50. 

2019

1. Galeotti C, Stephen-Victor E, Karnam A, Das M, Gilardin L, Maddur MS, Wymann S, Vonarburg C, Chevailler A, Dimitrov JD, Benveniste O, Bruhns P, Kaveri SV, Bayry J. Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE. J Allergy Clin Immunol. 2019 Aug;144(2):524-535.
2. Ray S, Da Costa R, Das M, Nandi D. Interplay of cold shock protein E with an uncharacterized protein, YciF, lowers porin expression and enhances bile resistance in Salmonella Typhimurium. J Biol Chem. 2019 Jun 7;294(23):9084-9099. 
3. Karnam A, Stephen-Victor E, Das M, Magy L, Vallat JM, Bolgert F, Simon-Loriere E, Kaveri SV, Sakuntabhai A, Bayry J. Does intravenous immunoglobulin therapy in Guillain-Barré syndrome patients interfere with serological Zika detection? Autoimmun Rev. 2019 Jun;18(6):632-633. 
4. Mukherjee S, Karnam A, Das M, Babu SPS, Bayry J. Wuchereria bancrofti filaria activates human dendritic cells and polarizes T helper 1 and regulatory T cells via toll-like receptor 4. Commun Biol. 2019 May 7;2:169.
5. Das M, Alzaid F, Bayry J. Regulatory T Cells under the Mercy of Mitochondria. Cell Metab. 2019 Feb 5;29(2):243-245.

2018

1. Sharma M*, Das M*, Stephen-Victor E, Galeotti C, Karnam A, Maddur MS, Bruneval P, Kaveri SV, Bayry J. Regulatory T cells induce activation rather than suppression of human basophils. Sci Immunol. 2018 May 25;3(23):eaan0829. (* Co-first authors)

2017

1. Stephen-Victor E, Karnam A, Fontaine T, Beauvais A, Das M, Hegde P, Prakhar P, Holla S, Balaji KN, Kaveri SV, Latgé JP, Aimanianda V, Bayry J. Aspergillus fumigatus Cell Wall α-(1,3)-Glucan Stimulates Regulatory T-Cell Polarization by Inducing PD-L1 Expression on Human Dendritic Cells. J Infect Dis. 2017 Dec 5;216(10):1281-1294. 
2. Stephen-Victor E*, Das M*, Sharma M, Galeotti C, Fohrer-Ting H, Sendid B, Darnige L, Terris B, Badoual C, Bruneval P, Kaveri SV, Bayry J. Demystification of enigma on antigen-presenting cell features of human basophils: data from secondary lymphoid organs. Haematologica. 2017 Jun;102(6):e233-e237. (* Co-first authors)
3. Maddur MS*, Stephen-Victor E*, Das M*, Prakhar P, Sharma VK, Singh V, Rabin M, Trinath J, Balaji KN, Bolgert F, Vallat JM, Magy L, Kaveri SV, Bayry J. Regulatory T cell frequency, but not plasma IL-33 levels, represents potential immunological biomarker to predict clinical response to intravenous immunoglobulin therapy. J Neuroinflammation. 2017 Mar 20;14(1):58. (* Co-first authors)
4. Das M, Galeotti C, Stephen-Victor E, Karnam A, Kaveri SV, Bayry J. Human basophils may not undergo modulation by DC-SIGN and mannose receptor-targeting immunotherapies due to absence of receptors. J Allergy Clin Immunol. 2017 Apr;139(4):1403-1404.
5. Saha C*, Das M*, Patil V, Stephen-Victor E, Sharma M, Wymann S, Jordi M, Vonarburg C, Kaveri SV, Bayry J. Monomeric Immunoglobulin A from Plasma Inhibits Human Th17 Responses In Vitro Independent of FcαRI and DC-SIGN. Front Immunol. 2017 Mar 14;8:275. (* Co-first authors)

2016

1. Stephen-Victor E, Sharma VK, Das M, Karnam A, Saha C, Lecerf M, Galeotti C, Kaveri SV, Bayry J. IL-1β, But Not Programed Death-1 and Programed Death Ligand Pathway, Is Critical for the Human Th17 Response to Mycobacterium tuberculosis. Front Immunol. 2016 Nov 4;7:465. 
2. Saha C*, Das M*, Stephen-Victor E, Friboulet A, Bayry J, Kaveri SV. Differential Effects of Viscum album Preparations on the Maturation and Activation of Human Dendritic Cells and CD4⁺ T Cell Responses. Molecules. 2016 Jul 14;21(7):912. (* Co-first authors)
3. Bhaskarla C, Das M, Verma T, Kumar A, Mahadevan S, Nandi D. Roles of Lon protease and its substrate MarA during sodium salicylate-mediated growth reduction and antibiotic resistance in Escherichia coli. Microbiology (Reading). 2016 May;162(5):764-776. 
4. Galeotti C, Hegde P, Das M, Stephen-Victor E, Canale F, Muñoz M, Sharma VK, Dimitrov JD, Kaveri SV, Bayry J. Heme oxygenase-1 is dispensable for the anti-inflammatory activity of intravenous immunoglobulin. Sci Rep. 2016 Jan 22;6:19592.

2015

1. Das M, Bhosale M, Wadhwa N, Ahmed SM, Bhaskarla C, Kumar A, Srinivasan N, Nandi D. Importance of Amino Acids, Gln-119 and Tyr-376, in the S1 Pocket of Escherichia coli Peptidase N in Determining Substrate Specificity. Protein Pept Lett. 2016;23(6):548-61.
2. Das M, Kaveri SV, Bayry J. Cross-presentation of antigens by dendritic cells: role of autophagy. Oncotarget. 2015 Oct 6;6(30):28527-8.
3. Chandrasekar BS, Yadav S, Victor ES, Majumdar S, Deobagkar-Lele M, Wadhwa N, Podder S, Das M, Nandi D. Interferon-gamma and nitric oxide synthase 2 mediate the aggregation of resident adherent peritoneal exudate cells: implications for the host response to pathogens. PLoS One. 2015 Jun 1;10(6):e0128301.

2013

Bhosale M, Kumar A, Das M, Bhaskarla C, Agarwal V, Nandi D. Catalytic activity of Peptidase N is required for adaptation of Escherichia coli to nutritional downshift and high temperature stress. Microbiol Res. 2013 Jan 15;168(1):56-64.

Funded Projects

• Title: Targeting the Epithelial Myosin Light Chain Kinase to Restore Barrier Integrity and Prevent Food Allergy in Metabolic Dysfunction
  Role: Principal Investigator (PI)
  Funding Agency: Anusandhan National Research Foundation (ANRF) - PM-ECRG
  Year & Duration: 2026-2029
  Sanctioned Amount: Approx. 65 lakhs
• Title: Investigating the Impact of Homeopathic Therapy on Clinical Metabolic Control and Systemic Inflammatory Markers in Patients of Stage III & IV Periodontitis with Diabetes: A Randomized Multi-Arm Clinical Trial
  Role: Co-Principal Investigator (Co-PI)
  Funding Agency: Central Council for Research in Homeopathy (CCRH)
  Project No.: CCRH 2975
  Year & Duration: 2025-2027
  Sanctioned Amount: Approx. 138 lakhs
• Title: Safety and Effectiveness of Homeopathy as an Add-On Treatment to Standard Care in the Management of Cardiac Arrhythmia (Safe-Home-Card): A Blinded Randomized Parallel Group, Exploratory, Feasibility Clinical Trial
  Role: Co-Principal Investigator (Co-PI)
  Funding Agency: Central Council for Research in Homeopathy (CCRH)
  Project No.: CCRH 3287
  Year & Duration: 2025-2028
  Sanctioned Amount: Approx. 100 lakhs
• Title: Mechanisms of Enhanced Food Allergy by Staphylococcus aureus Skin Colonization in Atopic Dermatitis
  Role: Co-Investigator
  Funding Agency: National Institutes of Health / National Institute of Allergy and Infectious Diseases (NIH/NIAID)
  Grant No.: R01AI175556
  Year & Duration: 2023-2028
  Sanctioned Amount: Approx $2.5 million

Publications

2026

• DongUk Lee, Meng-Ping Lu, Priya Rajamanimuthu, Mrinmoy Das, Enxhi Ferraj, Courtney Fisher, Peri Matatia, Chun-Wei Chen, Raif S. Geha, Caroline L. Sokol, Uthaman Gowthaman. Interleukin-4-producing type 2 innate lymphoid cells in the lymph node promote proallergic Tfh13 cell differentiation. 2026 Jul;59(7):1860–1875.e7. DOI: 10.1016/j.immuni.2026.04.015. PMID: 42161270.
• Chinmay Nitin Mokal, Mrinmoy Das, Sridhar Hannenhalli, Piyush Agrawal. Oral submucosal fibrosis: a comprehensive review on pathogenesis, diagnosis, therapeutics and computational advances. Frontiers in Cell and Developmental Biology. 2026 Jan;13:1754209. DOI: 10.3389/fcell.2025.1754209. PMID: 41660015.
• Suraj Chandrabhan Singh*, Sruthi Vijaya Retnakumar*, Mrinmoy Das*, Srini V. Kaveri, Mano Joseph Mathew, Jagadeesh Bayry. Intravenous immunoglobulin remodels innate immune cell communication and induces differential autophagy pathways in Kawasaki disease. Frontiers in Immunology. 2026 Feb;17:1753478. DOI: 10.3389/fimmu.2026.1753478. PMID: 41822482. (*Co-first authors)
• Darshika Pasi, Bijulal Aswathy, Mrinmoy Das, Piyush Agrawal. Breast cancer pathogenesis, diagnosis and treatment: a comprehensive review. Frontiers in Oncology. 2026 Mar;16:1773232. DOI: 10.3389/fonc.2026.1773232. PMID: 41971420.
• Mrinmoy Das^#, Raif S. Geha. Basophils in atopic dermatitis: Immunologic roles and clinical implications. Annals of Allergy, Asthma & Immunology. 2026 Feb;136(2):149–157. DOI: 10.1016/j.anai.2025.11.005. PMID: 41248845. (^# Corresponding author)

2025

• Mrinmoy Das^#, Mohammed Alasharee, Brian Woods, Saikat Mukherjee, Shira Kim, Megan Elkins, Jacqueline Ngo, Logan Magin, Maheshwor Timilshina, Juan Manuel Leyva-Castillo, Kenneth M. Murphy, Robert M. Anthony, Ana Flávia Santarine Laureano, George F. Murphy, Shannon McNamee, Frank Brombacher, Simon P. Hogan, Jerrold R. Turner, Shabnam Abtahi, Wanda Phipatanakul, Donald Y. M. Leung, Elena Goleva, Hans C. Oettgen, Mei Li, Janet Chou, Patrick M. Schlievert, Fred D. Finkelman, Raif S. Geha. aureus exposure during cutaneous antigen sensitization causes basophil- and interleukin-4-dependent exaggerated food anaphylaxis. Immunity. 2025 Nov;58(11):2769–2784.e6. DOI: 10.1016/j.immuni.2025.09.001. PMID: 41005294. (^#Corresponding author)
• Saikat Mukherjee, Raif S. Geha, Mrinmoy Das^#. The Mechanisms of Immunoglobulin E Sensitizations in Atopic Dermatitis. Immunology and Allergy Clinics of North America. 2025 Nov;45(4):535–546. DOI: 10.1016/j.iac.2025.06.006. PMID: 41136093. (^#Corresponding author)
• Erin Janssen, Mrinmoy Das*, Jordan Butts, Mohammed Alasharee, Saikat Mukherjee, Gabriela L. Lozano, Chandra Rao, Ashley F. Livingston, Brian Woods, Emily Smith, Zachary Peters, Elena Milin, Matthew A. Beamer, Hazel Wilkie, Juan Manuel Leyva-Castillo, Christy Kam, Ali Sobh, Mohamed Dasouki, Rima H. Wakim, Ghassan Dbaibo, Waleed Al-Herz, Talal A. Chatila, Fred D. Finkelman, Stephen Rakoff-Nahoum, Raif S. Geha. DOCK8 in T cells promotes Th17 and Treg cell functionality to restrain mucosal mast cells and limit susceptibility to oral anaphylaxis. 2025 Jul;58(7):1794–1810. (*Co-first authors)
• Subhashish Chakraborty, Pip Banerjee, Joel P. Joseph, Sanmoy Pathak, Taru Verma, Aagosh Kishor Karhale, Deepti Chandra, Mrinmoy Das, Pritam Saha, Dipankar Nandi. Functional loss of rffG and rfbB, encoding dTDP-glucose 4,6-dehydratase, alters colony morphology, cell shape, motility and virulence in Salmonella Typhimurium. Frontiers in Microbiology. 2025 May;16:1572117. DOI: 10.3389/fmicb.2025.1572117. PMID: 40469742.
• Mrinmoy Das, Tarun Keswani. Editorial: T and B cell immune dynamics in allergic response. Frontiers in Allergy. 2025 Feb;6:1558724. DOI: 10.3389/falgy.2025.1558724. PMID: 40012569.
• Melanie L. Conrad, Gabriela Barrientos, Xuejun Cai, Saikat Mukherjee, Mrinmoy Das, Emmanuel Stephen-Victor, Hani Harb. Regulatory T cells and their role in allergic disease. 2025 Jan;80(1):77–93. DOI: 10.1111/all.16326. PMID: 40497455.

2024

• Juan Manuel Leyva-Castillo*, Mrinmoy Das*, Maria Strakosha, Alex McGurk, Emilie Artru, Christy Kam, Mohammed Alasharee, Duane R. Wesemann, Michio Tomura, Hajime Karasuyama, Frank Brombacher, Raif S. Geha. IL-4 acts on skin-derived dendritic cells to promote the TH2 response to cutaneous sensitization and the development of allergic skin inflammation. Journal of Allergy and Clinical Immunology. 2024 Dec;154(6):1462–1471.e3. DOI: 10.1016/j.jaci.2024.06.021. PMID: 38996877. (*Co-first authors)
• Hazel Wilkie, Mrinmoy Das, Tyler Pelovitz, Wayne Bainter, Brian Woods, Mohammed Alasharee, Ali Sobh, Safa Baris, Sevgi Bilgic Eltan, Waleed Al-Herz, Mohamed-Ridha Barbouche, Imen Ben-Mustapha, Meriem Ben-Ali, Mohamed T. H. Sallam, Amany Awad, Sohilla Lotfy, Aisha El Marsafy, Moushira Ezzelarab, Michael Farrar, Brigitta A. R. Schmidt, Monali NandyMazumdar, Emma Guttman-Yassky, Anthony Sheets, Kelly M. Vidic, George Murphy, Patrick M. Schlievert, Janet Chou, Juan Manuel Leyva-Castillo, Erin Janssen, Maheshwor Timilshina, Raif S. Geha. Regulatory T-cell dysfunction and cutaneous exposure to Staphylococcus aureus underlie eczema in DOCK8 deficiency. Journal of Allergy and Clinical Immunology. 2024 Jul;154(1):143–156. DOI: 10.1016/j.jaci.2023.12.020. PMID: 38185418.
• Mrinmoy Das, Saikat Mukherjee, Raif S. Geha. Phosphodiesterase 4 Inhibitors, Basophils, and Atopic Dermatitis. Journal of Investigative Dermatology. 2024 May;144(5):924–926. DOI: 10.1016/j.jid.2023.12.025. PMID: 38441508.
• Mrinmoy Das^#, Raif S. Geha. Skin sensitization and food allergy. In: Encyclopedia of Food Allergy. Elsevier Ltd.; 2024. Book chapter. (^#Corresponding author)

2023

• Hazel Wilkie, Maheshwor Timilshina, Siti Rahmayanti, Mrinmoy Das, Tyler Pelovitz, Raif S. Geha. DOCK8 is essential for neutrophil mediated clearance of cutaneous S. aureus infection. Clinical Immunology. 2023 Sep;254:109681. DOI: 10.1016/j.clim.2023.109681. PMID: 37385324.
• Barbara Yang, Hazel Wilkie, Mrinmoy Das, Maheshwor Timilshina, Wayne Bainter, Brian Woods, Michelle Daya, Meher P. Boorgula, Rasika A. Mathias, Peggy Lai, Carter R. Petty, Edie Weller, Hani Harb, Talal A. Chatila, Donald Y. M. Leung, Lisa A. Beck, Eric L. Simpson, Tissa R. Hata, Kathleen C. Barnes, Wanda Phipatanakul, Juan-Manuel Leyva-Castillo, Raif S. Geha. The IL-4Rα Q576R polymorphism is associated with increased severity of atopic dermatitis and exaggerates allergic skin inflammation in mice. Journal of Allergy and Clinical Immunology. 2023 May;151(5):1296–1306.e7. DOI: 10.1016/j.jaci.2023.01.011. PMID: 36690254.

2021

• Juan-Manuel Leyva-Castillo, Mrinmoy Das, Jennifer Kane, Maria Strakosha, Sonal Singh, Daniel Sen Hoi Wong, Alexander R. Horswill, Hajime Karasuyama, Frank Brombacher, Lloyd S. Miller, Raif S. Geha. Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection. JCI Insight. 2021 Nov;6(21). DOI: 10.1172/jci.insight.149953. PMID: 34747366.
• Wayne Bainter, Vassilios Lougaris, Jacqueline G. Wallace, Yousef Badran, Rodrigo Hoyos-Bachiloglu, Zachary Peters, Hazel Wilkie, Mrinmoy Das, Erin Janssen, Abdallah Beano, Khaoula Ben Farhat, Christy Kam, Luisa Bercich, Paolo Incardona, Vincenzo Villanacci, Maria Pia Bondioni, Antonella Meini, Manuela Baronio, Phammela Abarzua, Silvia Parolini, Giulia Tabellini, Stefano Maio, Brigitta Schmidt, Jonathan D. Goldsmith, George Murphy, George Hollander, Alessandro Plebani, Janet Chou, Raif S. Geha. Combined immunodeficiency with autoimmunity caused by a homozygous missense mutation in inhibitor of nuclear factor κB kinase alpha (IKKα). Science Immunology. 2021 Sep;6(63). DOI: 10.1126/sciimmunol.abf6723. PMID: 34533979.
• Mrinmoy Das, Juan Manuel Leyva-Castillo, Raif S. Geha. Basophil: The cell that itches. Journal of Allergy and Clinical Immunology. 2021 Sep;148(3):708–709.
• Juan Manuel Leyva-Castillo, Mrinmoy Das, Emilie Artru, Juhan Yoon, Claire Galand, Raif S. Geha. Mast cell-derived IL-13 downregulates IL-12 production by skin dendritic cells to inhibit the TH1 cell response to cutaneous antigen exposure. Journal of Allergy and Clinical Immunology. 2021 Jun;147(6):2305–2315.e3. DOI: 10.1016/j.jaci.2020.11.036. PMID: 33316284.

2020

• Emmanuel Stephen-Victor, Mrinmoy Das, Anupama Karnam, Bruno Pitard, Jean-François Gautier, Jagadeesh Bayry. Potential of regulatory T-cell-based therapies in the management of severe COVID-19. European Respiratory Journal. 2020 Sep;56(3):2002182. DOI: 10.1183/13993003.02182-2020. PMID: 32616599.
• Erin Janssen, Mira Tohme, Jordan Butts, Sophie Giguere, Peter T. Sage, Francisco E. Velázquez, Christy Kam, Elena Milin, Mrinmoy Das, Ali Sobh, Salem Al-Tamemi, Francis W. Luscinskas, Facundo Batista, Raif S. Geha. DOCK8 is essential for LFA-1-dependent positioning of T follicular helper cells in germinal centers. JCI Insight. 2020 Aug;5(15). DOI: 10.1172/jci.insight.134508. PMID: 32573493.
• Mrinmoy Das, Emmanuel Stephen-Victor, Jagadeesh Bayry. Regulatory T cells do not suppress rather activate human basophils by IL-3 and STAT5-dependent mechanisms. 2020 Jun;9(1):1773193. DOI: 10.1080/2162402X.2020.1773193. PMID: 32923130.
• Anupama Karnam, Naresh Rambabu, Mrinmoy Das, Melissa Bou-Jaoudeh, Sandrine Delignat, Fabian Käsermann, Sébastien Lacroix-Desmazes, Srini V. Kaveri, Jagadeesh Bayry. Therapeutic normal IgG intravenous immunoglobulin activates Wnt-β-catenin pathway in dendritic cells. Communications Biology. 2020 Mar;3(1):96. DOI: 10.1038/s42003-020-0825-4. PMID: 32132640.
• Caroline Galeotti, Anupama Karnam, Mrinmoy Das, Srini V. Kaveri, Jagadeesh Bayry. Acid Stripping of Surface IgE Antibodies Bound to FcεRI Is Unsuitable for the Functional Assays that Require Long-Term Culture of Basophils and Entire Removal of Surface IgE. International Journal of Molecular Sciences. 2020 Jan;21(2):510. DOI: 10.3390/ijms21020510. PMID: 31941161.
• Mrinmoy Das, Anupama Karnam, Emmanuel Stephen-Victor, Laurent Gilardin, Bharat Bhatt, Varun Kumar Sharma, Naresh Rambabu, Veerupaxagouda Patil, Maxime Lecerf, Fabian Käsermann, Patrick Bruneval, Kithiganahalli Narayanaswamy Balaji, Olivier Benveniste, Srini V. Kaveri, Jagadeesh Bayry. Intravenous immunoglobulin mediates anti-inflammatory effects in peripheral blood mononuclear cells by inducing autophagy. Cell Death & Disease. 2020 Jan;11(1):50. DOI: 10.1038/s41419-020-2249-y. PMID: 31974400.

2019

• Caroline Galeotti, Emmanuel Stephen-Victor, Anupama Karnam, Mrinmoy Das, Laurent Gilardin, Mohan S. Maddur, Sandra Wymann, Cédric Vonarburg, Alain Chevailler, Jordan D. Dimitrov, Olivier Benveniste, Pierre Bruhns, Srini V. Kaveri, Jagadeesh Bayry. Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE. Journal of Allergy and Clinical Immunology. 2019 Aug;144(2):524–535.e8. DOI: 10.1016/j.jaci.2018.10.064. PMID: 30529242.
• Semanti Ray, Rochelle Da Costa, Mrinmoy Das, Dipankar Nandi. Interplay of cold shock protein E with an uncharacterized protein, YciF, lowers porin expression and enhances bile resistance in Salmonella Typhimurium. Journal of Biological Chemistry. 2019 Jun;294(23):9084–9099. DOI: 10.1074/jbc.RA119.008209. PMID: 30992363.
• Anupama Karnam, Emmanuel Stephen-Victor, Mrinmoy Das, Laurent Magy, Jean-Michel Vallat, Francis Bolgert, Etienne Simon-Loriere, Srini V. Kaveri, Anavaj Sakuntabhai, Jagadeesh Bayry. Does intravenous immunoglobulin therapy in Guillain-Barré syndrome patients interfere with serological Zika detection? Autoimmunity Reviews. 2019 Jun;18(6):632–633. DOI: 10.1016/j.autrev.2019.01.004. PMID: 30959213.
• Suprabhat Mukherjee, Anupama Karnam, Mrinmoy Das, Santi P. Sinha Babu, Jagadeesh Bayry. Wuchereria bancrofti filaria activates human dendritic cells and polarizes T helper 1 and regulatory T cells via toll-like receptor 4. Communications Biology. 2019 May;2:169. DOI: 10.1038/s42003-019-0392-8. PMID: 31098402.
• Mrinmoy Das, Fawaz Alzaid, Jagadeesh Bayry. Regulatory T Cells under the Mercy of Mitochondria. Cell Metabolism. 2019 Feb;29(2):243–245. DOI: 10.1016/j.cmet.2019.01.012. PMID: 30726757.

2018

• Meenu Sharma*, Mrinmoy Das*, Emmanuel Stephen-Victor, Caroline Galeotti, Anupama Karnam, Mohan S. Maddur, Patrick Bruneval, Srini V. Kaveri, Jagadeesh Bayry. Regulatory T cells induce activation rather than suppression of human basophils. Science Immunology. 2018 May;3(23). DOI: 10.1126/sciimmunol.aan0829. PMID: 29802207. (*Co-first authors)

2017

• Emmanuel Stephen-Victor, Anupama Karnam, Thierry Fontaine, Anne Beauvais, Mrinmoy Das, Pushpa Hegde, Praveen Prakhar, Sahana Holla, Kithiganahalli N. Balaji, Srini V. Kaveri, Jean-Paul Latgé, Vishukumar Aimanianda, Jagadeesh Bayry. Aspergillus fumigatus Cell Wall α-(1,3)-Glucan Stimulates Regulatory T-Cell Polarization by Inducing PD-L1 Expression on Human Dendritic Cells. Journal of Infectious Diseases. 2017 Dec;216(10):1281–1294. DOI: 10.1093/infdis/jix469. PMID: 28968869.
• Emmanuel Stephen-Victor*, Mrinmoy Das*, Meenu Sharma, Caroline Galeotti, Hélène Fohrer-Ting, Boualem Sendid, Luc Darnige, Benoit Terris, Cécile Badoual, Patrick Bruneval, Srini V. Kaveri, Jagadeesh Bayry. Demystification of enigma on antigen-presenting cell features of human basophils: data from secondary lymphoid organs. 2017 Jun;102(6)–e237. DOI: 10.3324/haematol.2016.163451. PMID: 28209657. (*Co-first authors)
• Mohan S. Maddur*, Emmanuel Stephen-Victor*, Mrinmoy Das*, Praveen Prakhar, Varun K. Sharma, Vikas Singh, Magalie Rabin, Jamma Trinath, Kithiganahalli N. Balaji, Francis Bolgert, Jean-Michel Vallat, Laurent Magy, Srini V. Kaveri, Jagadeesh Bayry. Regulatory T cell frequency, but not plasma IL-33 levels, represents potential immunological biomarker to predict clinical response to intravenous immunoglobulin therapy. Journal of Neuroinflammation. 2017 Mar;14(1):58. DOI: 10.1186/s12974-017-0818-5. PMID: 28320438. (*Co-first authors)
• Mrinmoy Das, Caroline Galeotti, Emmanuel Stephen-Victor, Anupama Karnam, Srini V. Kaveri, Jagadeesh Bayry. Human basophils may not undergo modulation by DC-SIGN and mannose receptor-targeting immunotherapies due to absence of receptors. Journal of Allergy and Clinical Immunology. 2017 Apr;139(4):1403–1404.e1. DOI: 10.1016/j.jaci.2016.09.062. PMID: 28088336.
• Chaitrali Saha*, Mrinmoy Das*, Veerupaxagouda Patil, Emmanuel Stephen-Victor, Meenu Sharma, Sandra Wymann, Monika Jordi, Cédric Vonarburg, Srini V. Kaveri, Jagadeesh Bayry. Monomeric Immunoglobulin A from Plasma Inhibits Human Th17 Responses In Vitro Independent of FcαRI and DC-SIGN. Frontiers in Immunology. 2017 Mar;8:275. DOI: 10.3389/fimmu.2017.00275. PMID: 28352269. (*Co-first authors)

2016

• Emmanuel Stephen-Victor, Varun Kumar Sharma, Mrinmoy Das, Anupama Karnam, Chaitrali Saha, Maxime Lecerf, Caroline Galeotti, Srinivas V. Kaveri, Jagadeesh Bayry. IL-1β, But Not Programed Death-1 and Programed Death Ligand Pathway, Is Critical for the Human Th17 Response to Mycobacterium tuberculosis. Frontiers in Immunology. 2016 Nov;7:465. DOI: 10.3389/fimmu.2016.00465. PMID: 27867382.
• Chaitrali Saha*, Mrinmoy Das*, Emmanuel Stephen-Victor, Alain Friboulet, Jagadeesh Bayry, Srini V. Kaveri. Differential Effects of Viscum album Preparations on the Maturation and Activation of Human Dendritic Cells and CD4+ T Cell Responses. 2016 Jul;21(7):912. DOI: 10.3390/molecules21070912. PMID: 27428940. (*Co-first authors)
• Chetana Bhaskarla, Mrinmoy Das, Taru Verma, Anujith Kumar, S. Mahadevan, Dipankar Nandi. Roles of Lon protease and its substrate MarA during sodium salicylate-mediated growth reduction and antibiotic resistance in Escherichia coli. Microbiology (Reading). 2016 May;162(5):764–776. DOI: 10.1099/mic.0.000271. PMID: 26944926.
• Caroline Galeotti, Pushpa Hegde, Mrinmoy Das, Emmanuel Stephen-Victor, Fernando Canale, Marcos Muñoz, Varun K. Sharma, Jordan D. Dimitrov, Srini V. Kaveri, Jagadeesh Bayry. Heme oxygenase-1 is dispensable for the anti-inflammatory activity of intravenous immunoglobulin. Scientific Reports. 2016 Jan;6:19592. DOI: 10.1038/srep19592. PMID: 26796539.
• Mrinmoy Das, Manoj Bhosale, Nitin Wadhwa, Syed M. Ahmed, Chetana Bhaskarla, Anujith Kumar, Narayanaswamy Srinivasan, Dipankar Nandi. Importance of Amino Acids, Gln-119 and Tyr-376, in the S1 Pocket of Escherichia coli Peptidase N in Determining Substrate Specificity. Protein and Peptide Letters. 2016;23(6):548–561. DOI: 10.2174/0929866523666160301122553. PMID: 26927617.

2015

• Mrinmoy Das, Srini V. Kaveri, Jagadeesh Bayry. Cross-presentation of antigens by dendritic cells: role of autophagy. 2015 Oct;6(30):28527–28528. DOI: 10.18632/oncotarget.5268. PMID: 26337341.
• Bhagawat S. Chandrasekar, Shikha Yadav, Emmanuel S. Victor, Shamik Majumdar, Mukta Deobagkar-Lele, Nitin Wadhwa, Santosh Podder, Mrinmoy Das, Dipankar Nandi. Interferon-gamma and nitric oxide synthase 2 mediate the aggregation of resident adherent peritoneal exudate cells: implications for the host response to pathogens. PLoS ONE. 2015 Jun;10(6). DOI: 10.1371/journal.pone.0128301. PMID: 26029930.

2013

• Manoj Bhosale, Anujith Kumar, Mrinmoy Das, Chetana Bhaskarla, Vikas Agarwal, Dipankar Nandi. Catalytic activity of Peptidase N is required for adaptation of Escherichia coli to nutritional downshift and high temperature stress. Microbiological Research. 2013 Jan;168(1):56–64. DOI: 10.1016/j.micres.2012.06.003. PMID: 22766257.

• 2026: Selected as a Young Investigator, Young Investigators’ Meeting (YIM), India
• 2016: Raman-Charpak Fellowship, Indo-French Centre for the Promotion of Advanced Research (IFCPAR/CEFIPRA), Governments of India and France
• Associate Editor: Frontiers in Molecular Medicine (2025-Present)
• Topic Editor: Frontiers in Allergy (2023-Present)
• Editorial Board Member: Journal of Clinical Pathology and Research (2024-Present)
• Invited Seminar, Indian Institute of Science (IISc), Bengaluru – 2026
• Plenary Lecture, 12th EMBRN Conference, Vienna, Austria – 2026
• Invited Seminar, National Centre for Cell Science (NCCS), Pune – 2026
• Scientific Presentation, 52nd IMMUNOCON – 2025

PhD Scholars

• Name: Shreya Ashok Bhandari
  Email: sb8625@srmist.edu.in
  Education: M.Sc. in Biochemistry
  Area of interest: Allergy and Inflammation, Immunology
• Name: Priti Kumari
  Email: pk2131@srmist.edu.in
  Education: M.Sc. in Human Genetics and Molecular Biology
  Area of interest: Immunology, Allergy and Inflammation

Availability: Available

Research Area: Barrier immunology, allergy and inflammation, epithelial biology, skin-gut immune axis, mucosal immunology, host-microbiota and host-pathogen interactions, and host-directed therapeutics.

Number of Positions: 1

Eligibility / Preferred Background: Candidates with an M.Sc. or equivalent postgraduate degree in Immunology, Biotechnology, Microbiology, Biochemistry, Life Sciences, Biomedical Sciences, or related disciplines. Candidates should have basic knowledge of immunology and infection biology. NET/GATE qualification and prior laboratory/research experience are preferred.

Mode of Registration: Full-time