Shiny PJ

Shiny PJ

Biomedical Researcher
Qualification : Doctor of Philosophy
Email : shinyp@srmist.edu.in

Dr. Shiny is a biomedical researcher with experience in nanobiotechnology, biomaterials, tissue engineering, and regenerative medicine. Her research focuses on developing bioactive biomaterials, advanced scaffolds, and nanoparticle-based therapeutic strategies for tissue repair, wound healing, and chronic disease management, with an emphasis on translating innovative biomaterial and stem cell-based approaches toward regenerative healthcare.

Her work includes the development of bioactive nanofibrous matrices for dermal reconstruction, wound healing, and burn regeneration, along with the investigation of bioactive ceramics and nanoparticle-based approaches for biomedical applications. These studies have established expertise in biomaterial design, scaffold engineering, cell–biomaterial interactions, and tissue regeneration.

Building on this multidisciplinary foundation, her future research will integrate biomaterials, stem cells, extracellular matrix engineering, nanotechnology, and three-dimensional tissue models to develop biomimetic platforms that recapitulate the native tissue microenvironment.

The long-term goal is to translate advanced biomaterial and stem cell-based approaches into innovative regenerative strategies for reproductive health, infertility, and restoration of tissue function.

  • Ph.D in Nanobiotechnology
  • Mar. 2023 – Present — Assistant Professor (Research), SRMIST
  • Jan. 2020 – Dec. 2022 — DBT- Research Associate, IIT Madras,
  • Oct. 2018 – Dec. 2019 — Research Coordinator
  • Sep. 2016 – Sep. 2018 — NPDF, SERB, CSIR-CLRI, Chennai
  • Nanobiotechnology; biomaterials; tissue engineering; regenerative medicine; bioactive scaffolds; nanoparticle-mediated therapies; dermal tissue regeneration; wound healing and regenerative medicine.

Funded Projects

  • Title: Effect of Homeopathic Preparation-Enriched Scaffolds in Burn Wound Management
    Role:  Principal Investigator
    Funding Agency:  Ministry of AYUSH, Govt. of India
    Year & Duration:  2025; 3 years
    Sanctioned Amount:  ₹36,08,945/-
  • Title: Investigating the Impact of Homeopathic Therapy on Clinical Metabolic Control and Systemic Inflammatory Markers in Patients of Stage III & IV Periodontitis with Diabetes: A Randomized Multi-Arm Clinical Trial
    Role: Co-Principal Investigator
    Funding Agency: Central Council for Research in Homeopathy (CCRH)
    Project No.: CCRH 2975
    Year & Duration: 2025-2027
    Sanctioned Amount:  1,38,22,296/-
  • Title: Development of a Dermal Skin Substitute for Dermal Tissue Regeneration
    Role: Supervisor
    Funding Agency: SRM Institute of Science and Technology (SRMIST)
    Year & Duration: 2025–2028 (3 years)
    Sanctioned Amount: ₹5,00,000/-
  • Title: Smart Health Monitoring: Laser-Printed Nanomaterial-Modified Urine Test Strips with IoT Integration Role: Co-Investigator
    Funding Agency: SRM Institute of Science and Technology (SRMIST)
    Year & Duration: 2024–2026 (2 years)
    Sanctioned Amount: ₹2,80,000/-
  • Title: Teardrop-Sepsis: A Microfluidic point-of-care with smartphone integration for early sepsis risk assessment. Role: Co-Investigator
    Funding Agency: SRM Institute of Science and Technology (SRMIST)
    Year & Duration: 2024–2026 (2 years)
    Sanctioned Amount: ₹2,30,000/-

Publications

  • Muthukumar, K.A., Nandi, D., Ranjan, P., Krithika Ramachandran, Shiny PJ et al. Integrating electrocardiogram and fundus images for early detection of cardiovascular diseases. Scientific Reports. 2025;15:4390. doi:10.1038/s41598-025-87634-z.
  • Haridoss, M., Nandi, D., Rajesh Lenin, R., John, S. P., Anantharaman, V. V., & Janardhanan, R. Health-seeking behavior and its determinants for non-communicable diseases in India—a systematic review and meta-analysis. Frontiers in Public Health. 2025;13:1580824.
  • Shiny PJ, Nagarajan R. A Review on Biomaterials Fabricated for Cardiac Tissue Engineering Using Decellularized Extracellular Matrix. Regenerative Engineering and Translational Medicine. 2024. doi:10.1007/s40883-024-00341-5.
  • Aravinthan, M., Gopal, S., Shiny, P.J. et al. Gene Expression Overlap Between Ear Wax and Keratosis Obturans: Insights into a Potential Pathogenic Link. Indian J Otolaryngol Head Neck Surg. 2025;77:5577–5583. doi:10.1007/s12070-025-06020-3.
  • Solomon, T. C., Gopal, S., Pal, S., Shiny, P. J., Ravisankar, M., & Balaji, C. R. K. Role of estrogen receptors as prognostic tool in chronic sinusitis. Journal of Rare Cardiovascular Diseases. 2025. doi:10.61336/jrcd/25-S5-08.
  • A Sathvika, C ND, PJ Shiny, Ravichandran S, Kumar JS. Unveiling the Veiled: Enteroviral Meningitis Mimicking Idiopathic Intracranial Hypertension. Cureus. 2024;16(7):e63884. doi:10.7759/cureus.63884.
  • Mani, Mahendrakumar, Aruna Sharmili Sundararaj, Khalid A. Al-Ghanim, Shiny PJ, Kuppusamy Elumalai, Marcello Nicoletti, and Marimuthu Govindarajan. Rapid synthesis of copper nanoparticles using Nepeta cataria leaves: An eco-friendly management of disease-causing vectors and bacterial pathogens. Green Processing and Synthesis. 2023;12:1;20230022. doi:10.1515/gps-2023-0022.
  • Sivasankar Koppala, Shiny PJ, Balan Ramdas, Lokesh Budigi, Sathishkumar Munusamy, Parasuraman Karthikeyan, Chirag Batukbhai Godiya, Suresh Yadav Chandragiri, Tejraj M. Aminabhavi, Kaijiao Duan, Kangqiang Li, Lei Xu, Yi Xia, Sasikumar Swamiappan. Glowing combustion synthesis, characterization and biomedical properties of Sr-hardystonite (Sr2ZnSi2O7) powders. Ceramics International. 2022;48:16;23649–23656. doi:10.1016/j.ceramint.2022.05.013.
  • Sivasankar Koppala, Budigi Lokesh, Ramdas Balan, Shiny Punalur John, Jonnagaddala Harathi, Sathishkumar Munusamy, Parasuraman Karthikeyan, Nagarajan Padmavathy, Lei Xu, Sasikumar Swamiappan. A simple energy efficient sol-gel combustion production of strontium orthosilicate and its biomedical study. Materials Science for Energy Technologies. 2022;5:366–374. doi:10.1016/j.mset.2022.09.003.
  • Shiny PJ, Vimala D Mohan, Grace Felciya Sekar Jeyakumar, Giriprasath Ramanathan, Pedro Fardim, Uma Tiruchirapalli Sivagnanam. In vitro and in vivo evaluation of poly-3-hydroxybutyric acid-sodium alginate as a core-shell nanofibrous matrix with arginine and bacitracin-nanoclay complex for dermal reconstruction of excision wound. International Journal of Biological Macromolecules. 2021;168:46–58. doi:10.1016/j.ijbiomac.2020.12.025.
  • Vimala Devi Mohan, Liji Sobhana S.S, Punalur John Shiny, Giriprasath Ramanathan, Grace Felciya Sekar Jeyakumar, Pedro Fardim, Uma Tiruchirapalli Sivagnanam. Durable nanofibrous matrices augmented with hydrotalcite-like compounds for cutaneous regeneration of burn wounds. Applied Clay Science. 2020;187:105476. doi:10.1016/j.clay.2020.105476.
  • Nikhil KG, Jayakumar KT, Shiny PJ, Ramya NK, Kumar JS. Neutrophil lymphocyte ratio and heart type fatty acid binding protein as a prognostic marker in Myocardial infarction within 48 hours of admission. The Egyptian Heart Journal. 2024. doi:10.1186/s43044-024-00489-z.
  • Aravinthan, M., Gopal, S., Shiny, P.J. et al. Gene Expression Overlap Between Ear Wax and Keratosis Obturans: Insights into a Potential Pathogenic Link. Indian J Otolaryngol Head Neck Surg. 2025. doi:10.1007/s12070-025-06020-3.
  • G Sekar, S Sugumar, RS Kumar, PJ Shiny, A Muherjee, N Chandrasekaran. Active compounds encapsulated nanoemulsion systems and their applications: A Review. Journal of Bionanoscience. 2017;10:6;435–443. doi:10.1166/jbns.2016.1401.
  • Shiny PJ, N Chandrasekaran, A Mukherjee. Mitochondria mediated apoptosis induced by noble metal nanoparticles in lung carcinoma cells. RSC Advances. 2016;6:27775–27787. doi:10.1039/C5RA27185A.
  • J. Shiny, Amitava Mukherjee, N. Chandrasekaran. Haemocompatibility assessment of synthesised platinum nanoparticles and its implication in Biology. Bioprocess and Biosystems Engineering. 2014;37:6;991–997. doi:10.1007/s00449-013-1069-1.
  • Sindhu Priya Dhas, Shiny P.J, Sudheer Khan, Amitava Mukherjee, N. Chandrasekaran. Toxic behavior of silver and zinc oxide nanoparticles on environmental microorganisms. Journal of Basic Microbiology. 2014;54:9;916–927. doi:10.1002/jobm.201200316.
  • SP Dhas, SP John, A Mukherjee, N Chandrasekaran. Autocatalytic growth of biofunctionalized antibacterial silver nanoparticles. Biotechnology and Applied Biochemistry. 2014;61:3;322–332. doi:10.1002/bab.1161
  • Shiny PJ, Amitava Mukherjee, Natarajan Chandrasekaran. Padina tetrastomatica: A potential source for the synthesis of silver nanoparticles and its antibacterial efficiency. Advanced Science, Engineering and Medicine. 2013;5:9;926–931. doi:10.1166/asem.2013.1301.
  • Shiny, Amitava Mukherjee, N Chandrasekaran. Marine algae mediated synthesis of the silver nanoparticles and its antibacterial efficiency. International Journal of Pharmacy and Pharmaceutical Sciences. 2013;5:2;239–241.
  • S. Suresh Kumar, P.J. Shiny, C. H. Anjali, Jayakumar Jerobin, Katrin Margulis Goshen, Shlomo Magdassi & Amitava Mukherjee, N. Chandrasekaran. Distinctive effects of nano-sized permethrin in the environment. Environmental Science and Pollution Research. 2013;20(4):593–602. doi:10.1007/s11356-012-1161-0.
  • Joyce Nirmala, Shiny PJ, Vinita Ernest, Sindhu Priya Dhas, A. Samundeeswari, Amitava Mukherjee, and N. Chandrasekaran. A review on safer means of nanoparticle synthesis by exploring the prolific marine ecosystem as a new thrust area in nanopharmaceutics. International Journal of Pharmacy and Pharmaceutical Sciences. 2013;5:1;23–29.
  • Vinita Ernest, J. Shiny, Amitava Mukherjee, N. Chandrasekaran. Silver nanoparticles: a potential nanocatalyst for the rapid degradation of starch hydrolysis by α-amylase. Carbohydrate Research. 2012;352:60–64. doi:10.1016/j.carres.2012.02.009.
  • Samundeeswari, Sindhu Priya Dhas, M. Joyce Nirmala, Shiny PJ, Amitava Mukherjee, N. Chandrasekaran. Biosynthesis of silver nanoparticles using actinobacteria Streptomyces albogriseolus and its antibacterial activity. Biotechnology and Applied Biochemistry. 2012;59:6;503–507. doi:10.1002/bab.1054.
  • N. George, P. J. Shiny, J. Miriam, C. A. Nancy, K. R. Dhanasekar & J. Peedicayil. Inhibitory effect of anticholinergics on the contraction of isolated caprine urinary bladder detrusor muscle. Autonomic & Autacoid Pharmacology. 2010;30:173–177. doi:10.1111/j.1474-8673.2009.00447.x.

PhD Scholars

  • Name: Kamalipriya S S
    Email: ks9915@srmist.edu.in
    Education: MSc. Applied Microbiology
    Area of interest: Regenerative Medicine
  • Name : Waseem Firose M
    Email : waseemfm@srmist.edu.in
    Education: MSc Stem Cell & Regenerative Biology
    Area of interest: Regenerative Medicine

Availability: Available

Research Area: Biomaterial for disease modeling, Hydrogels/ Nanomaterial,

Number of Positions: 1

Eligibility / Preferred Background: Candidates with an M.Sc. or equivalent postgraduate degree in Biotechnology, Biomedical Sciences, Life Sciences, Biochemistry, Bioengineering, or related disciplines are eligible to apply. Candidates should have a basic understanding of biomaterials, stem cell biology, tissue engineering, and regenerative medicine. Familiarity with cell culture, biomaterial characterization, molecular biology, or related laboratory techniques will be an advantage. NET/GATE qualification and prior laboratory or research experience are preferred.

Mode of Registration: Full-time